CASCADE-CATALYSED NANOCARRIER DEGRADATION FOR REGULATING METABOLISM HOMEOSTASIS AND ENHANCING DRUG PENETRATION ON BREAST CANCER

Cascade-catalysed nanocarrier degradation for regulating metabolism homeostasis and enhancing drug penetration on breast cancer

Abstract The abnormal structure of tumor vascular seriously hinders the delivery and deep penetration of drug in tumor therapy.Herein, an integrated and tumor microenvironment (TME)-responsive nanocarrier is designed, which can dilate vessle and improve the drug penetration by in situ releasing nitric oxide (NO).Briefly, S-nitroso-glutathione (GSNO

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The Place of Culture in the Current International Relations

Culture and international relations easily appear to be mutually contradictory terms.To speak of "culture" is to invoke the creative do not enter under construction sign capacities of human beings, to point, for example, to the constitutive role of values and visions, to the power of language and aesthetic expression, to communities great and small

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Cross-finger subdermal pocketplasty as a salvage procedure for thumb tip replantation without vascular anastomosis: a case report

Objectives Fingertip amputation is often encountered in emergency departments, especially in hospitals located near industrial areas.Replantation of the fingertip can be considered when the normal architecture is preserved in cases of sharp amputation.The goal of replantation is iphone 12 price georgia to preserve cosmesis and function, especially

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